Synthesis and physicochemical properties of new 1N o‐(m‐ and p‐) bromobenzyl substituted derivatives of 5‐(aminodialkyl)methylcytosine
Authors:
Dorota Prukala
Affiliation:
Faculty of Chemistry, Adam Mickiewicz University, Grunwaldzka 6, 60‐780 Poznań
Abstract:
Simple alkylation of 5‐(aminodialkyl)methylcytosine a‐d gives twelve new, potentially biologically active 1N o‐(m‐ or p‐) bromobenzyl derivatives of 5‐substituted cytosine 1‐12 with high regioselectivity. The structures of all compounds have been confirmed by elemental analysis, IR, 1H NMR and 13C NMR spectroscopic measurements.