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A facile one‐pot synthesis of 2‐amino‐4‐arylbenzo[h]quinoline‐3‐carbonitrile derivatives without catalyst
Authors:Shujiang Tu  Runhong Jia  Junyong Zhang  Yan Zhang  Bo Jiang
Institution:1. Department of Chemistry, Xuzhou Normal University, Key Laboratory of Biotechnology on Medical Plant, Xuzhou;2. Jiangsu, 221116, P. R. China
Abstract: chemical structure image A series of 2‐amino‐4‐arylbenzoh]quinoline‐3‐carbonitrile derivatives were synthesized by one‐pot condensation of aromatic aldehyde, a‐naphthylamine and malononitrile in ethanol without catalyst. This multicomponent reaction has the notable advantages of short route, high yield and convenient operation.
Keywords:
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