One-pot synthesis of 4,5-disubstituted 1,2,3-(NH)-triazoles by silica supported-zinc bromide in the aerobic condition |
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| Authors: | Ali Keivanloo Mohammad Bakherad Sayed Ali Naghi Taheri Shahrzad Samangooei |
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| Institution: | School of Chemistry, Shahrood University of Technology, Daneshgah avenue, Shahrood 3619995161, Iran |
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| Abstract: | An efficient one-pot cross-coupling/1,3-dipolar cycloaddition sequence was developed for a convenient synthesis of 4,5-disubstituted-1,2,3-(NH)-triazoles, starting from various acid chlorides, terminal alkynes and sodium azide in the presence of silica supported-zinc bromide under aerobic conditions. |
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