EPR SPECTROSCOPY OF ETHIDIUM NITRENE AND PROFLAVINE NITRENE COORDINATED TO SELF-COMPLEMENTARY DINUCLEOTIDE MINI-DUPLEXES |
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| Authors: | S Soundaramani Karl Haider Matthew S Platz |
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| Institution: | Department of Chemistry, The Ohio State University, Columbus, OH 43210, USA |
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| Abstract: | Abstract— Photolysis of ethidium azide ( lb ) and proflavine azide ( 2b ) immobilized in glassy media at 77 K produces triplet EPR spectra of the corresponding triplet nitrenes lc and 2c . The resonance field positions of the nitrenes are shifted by the presence of self-complementary dinucleotides. Control experiments indicated that the interaction of lc and 2c with CPG mini-duplexes is consistent with intercalation. |
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