Developments in analytical fourier-transform mass spectrometry

Development of a differentially-pumped, dual-cell geometry, coupled with the evolution of pulsed-laser desorption and Cs⁺-secondary-ion mass spectrometric (s.i.m.s.) desorption methods, has improved the analytical utility of Fourier-transform mass spectrometry (F.t.m.s.). A survey of applications and performances obtained in our laboratories is presented. Among the topics covered are ultra-high-resolution electron-impact and chemical-ionization mass spectra, gas chromatography/F.t.m.s. performance, pulsed Cs⁺-s.i.m.s./F.t.m.s. with cooled liquid matrices and solid samples, laser desorption/F.t.m.s. and accurate mass measurements taken under each of these modes of operation.