The acidity and solubility constants of tetracyclines in aqueous solutions |
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| Authors: | B.M. Ahmed R.D. Jee |
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| Affiliation: | The School of Pharmacy, University of London, 29-39 Brunswick Square, London, WC1N 1AX Great Britain |
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| Abstract: | Solubility measurements over the pH range 2.6–7.6 for tetracycline, chlortetracycline, dimethylchlortetracycline and oxytetracycline are used to determine thermodynamic values for the solubility constant and the first and second acidity constants of these compounds. |
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