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Novel multicomponent reaction for the combinatorial synthesis of 2-imidazolines
Authors:Bon Robin S  Hong Chongen  Bouma Marinus J  Schmitz Rob F  de Kanter Frans J J  Lutz Martin  Spek Anthony L  Orru Romano V A
Institution:Department of Chemistry, Vrije Universtiteit Amsterdam, De Boelelaan 1083, 1081 HV, Amsterdam, The Netherlands.
Abstract:reaction: see text] The three-component condensation between an amine, an aldehyde, and an alpha-acidic isocyanide efficiently provides substituted 2-imidazolines in a one-pot reaction under mild conditions.
Keywords:
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