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New conversion of Friendl(a)nder reaction of 3-amino-lH-benzo[f]chromene-2-carbonitriles with cyclohexanone
Authors:Jia Rong Li  Li Jun Zhang  Xi Quan Yang  Qing Li  Dong Wang  Chun Xia Wang  Da Xin Shi  Qi Zhang
Abstract:Two different skeletons of heterocyclic compounds, quinoline and quinazolinone analogs could be obtained by a novel one-potsynthesis from substituted 3-amino-lH-benzo[f]chromene-2-carbonitrile derivatives and cyclohexanone in DMF in the catalyst ofanhydrous zinc chloride under reflux. A plausible mechanism was proposed.
Keywords:Friedlander cyclocondensation  Quinoline and quinazolinone analogs  New conversion
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