微波促进下1-芳甲酰基-4-（2’-苯并呋喃甲酰基）氨基硫脲及其衍生物的合成

微波辐射条件下，首先由2-苯并呋喃甲酰氯在相转移条件下依次与硫氰酸铵和 芳甲酰肼反应合成了一系列1-芳甲酰基-4-（2’-苯并呋喃甲酰基）氨基硫脲，进 一步在微波辐射的条件下由这些氨基硫脲分别与碘酸钾、醋酸或醋酸汞等试剂作用 高产率地制得了1-芳甲酰基-4-（2’-苯并呋喃甲酰基）氨基脲、2-芳基-5-（2’- 苯并呋喃甲酰胺基）-1，3，4-噻二唑和2-芳基-5-（2’-苯并呋喃甲酰胺基）-1， 3，4-（口恶）二唑。

Microwave-Promoted Synthesis of 1-Aryol-4-(2''-benzofurancarbonyl)- thiosemicarbazides and Their Derivatives

l-Aroyl-4-( 2'-benzofurancarbonyl)-thiosemicarbazides were synthesized by the reactions of 2-benzofurancarbonyl chloride with ammonium thiocyanate and arylcarboxylic acid hydrazides under phase transfer catalysis and microwave irradiation. Treatment of the resulting thiosemicarbazides with potassium iodate, acetic acid or mercuric acetate under microwave irradiation gave l-aroyl-4-(2'- benzofurancarbonyl)-semicarbazides, 2-aryl-5-(2'-benzofurancarboxamido)- l, 3, 4-thiadiazoles and 2-aryl-5-(2'-benzofurancarboxamido)-l, 3, 4- oxadiazoles in high yields, respectively.