Spirocyclohexadienones: XII. Dienone-phenol rearrangement of 1-substituted 2-azaspiro[4.5]undeca-1,6,9-trienes and their analogs |
| |
Authors: | V A Glushkov E V Rotermel’ T F Odegova Yu V Shklyaev |
| |
Institution: | 1.Institute of Technical Chemistry, Ural Division,Russian Academy of Sciences,Perm,Russia;2.Perm State Pharmaceutical Academy,Perm,Russia |
| |
Abstract: | Hydrolytic cleavage of 1-substituted 2-azaspiro4.5]undeca-1,6,9-trienes in acid medium is accompanied by dienone-phenole
rearrangement with formation of substituted N-2-(p-hydroxyphenyl)ethyl] carboxylic acid amides. 1,2-Dimethoxy-3-oxo-15-phenyl-14-azadispiro5.1.5.2]pentadeca-1,4,14-triene
and 2′-R-7a′-methyl-3a′,4′,5′,6′,7′,7a′-hexahydrospirocyclohexa2,5]diene-1,3′-indol]-4-ones undergo analogous cleavage. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|