A study of the electrocatalytic oxidation of aspirin on a nickel hydroxide-modified nickel electrode |
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Authors: | S Majdi A Jabbari H Heli |
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Institution: | (1) Department of Chemistry, Faculty of Science, K. N. Toosi University of Technology, P.O. Box 16315-1618, Tehran, Iran;(2) Institute of Biochemistry and Biophysics, University of Tehran, P.O. Box 13145-1384, Tehran, Iran |
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Abstract: | The electrocatalytic oxidation of aspirin has been investigated on a nickel oxide-modified nickel electrode in alkaline solution.
The process of oxidation and its kinetics have been investigated by using cyclic voltammetry, chronoamperometry, and electrochemical
impedance spectroscopy techniques and also steady-state polarization measurements. Voltammetric studies have indicated that
in the presence of aspirin, the anodic peak current of low-valence nickel species increases, followed by a decrease in the
corresponding cathodic current. This indicates that aspirin was oxidized on the redox mediator immobilized on the electrode
surface via an electrocatalytic mechanism. The rate constant of the catalytic oxidation of aspirin and the electron transfer
coefficient have been found to be 1.15×105 cm3 mol−1s−1 and 0.49, respectively. Impedance measurements show that aspirin is diffused into the bulk of the modifier film, and the
oxidation process of aspirin occurs in the bulk of nickel oxide film. It has been shown that by using this modified electrode,
aspirin can be determined with a detection limit of 4.8×10−5 and successfully applied for determination of aspirin in tablet. |
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Keywords: | Aspirin Acetylsalicylic acid Nickel Modified electrode Electrocatalysis Impedance spectroscopy |
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