Entropic compression of interacting DNA loops |
| |
Authors: | Sankararaman Sumithra Marko John F |
| |
Institution: | Department of Physics, University of Illinois at Chicago, 60607, USA. sumithra@uic.edu |
| |
Abstract: | We solve a model for the equilibrium folding of DNA via the formation of randomly placed (nonspecific) loops. We find that the loop rearrangement entropy drives a significant reduction in loop size as more loops form. The reduction of the most probable loop size occurs over a wide range of forces and is enhanced by interloop cooperativity, indicating that it should be observable in single DNA experiments. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|