A facile and improved synthesis of desomorphine and its deuterium-labeled analogue |
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| Authors: | Sankareswaran Srimurugan Chi-Ju Su Hun-Chi Shu Kaliyappan Murugan Chinpiao Chen |
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| Affiliation: | (1) Department of Chemistry, National Dong Hwa University, Soufeng, Hualien, 974, Taiwan, R.O.C; |
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| Abstract: | Abstract This work describes a convenient and improved process for the synthesis of desomorphine from codeine. The proposed method affords the highly pure opiate without the aid of chromatographic purification, and provides a simple route for the synthesis of [2H3] deuterium-labeled desomorphine. |
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