Oxidative Ammonolysis of Dialkylpyridines

The cluster approach was used to simulate the chemisorption of dialkylperidines on the surface of a vanadium oxide catalyst, involving active centers of various nature, and to assess the enthalpy of proton abstraction from the alkyl substituents. Under oxidative ammonolysis conditions, the order of the transformation of the substituents in unsymmetrical dialkylpyridines into the cyano group is determined by the enthalpy of their deprotonation.__________Translated from Zhurnal Obshchei Khimii, Vol. 75, No. 1, 2005, pp. 159–163.Original Russian Text Copyright © 2005 by Vorob’ev, Sembaev.