The synthesis of difluoro[1]benzothieno[2,3-c]quinolines and their N-methyl quaternary salts |
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Authors: | Jiann-Kuan Luo Steven L. Castle Raymond N. Castle |
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Abstract: | A series of difluoro[1]benzothieno[2,3-c]quinolines has been prepared by photocyclization of the appropriate carboxamides. The lactams obtained were converted into the corresponding chloro derivatives which were catalytically dechlorinated into the difluoro[1] benzothieno[2,3-c]quinolines. The latter compounds were transformed into the N-methyl quaternary salts. |
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