Abstract: | Several novel 2-pyridones were synthesized in good yields from a simple one-pot reaction by the condensation of different substituted chalcones and malonamide using sodium ethoxide in ethanol at room temperature. The structures of these 2-pyridones were elucidated from their 1H, 13C and infrared spectral data as well as their elemental analysis. Different 2-pyridones tautomers were obtained as the solvent of crystallization changes. |