| 嗜硫色谱纯化抗体技术的研究进展 |
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| 引用本文： | 刘玄,宋宏新.嗜硫色谱纯化抗体技术的研究进展[J].色谱,2006,24(1):88-92. |
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| 作者姓名： | 刘玄 宋宏新 |
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| 作者单位： | Life Science & Engineering College, Shaanxi University of Science &Technology, Xianyang 712081, China |
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| 摘 要： | 嗜硫色谱在高盐环境下对抗体及其他某些蛋白质产生特异性吸附,再在低盐条件下洗脱,可获得高纯度及高回收率的蛋白质产品,是一种新型蛋白质纯化技术。该文对嗜硫色谱及其在抗体纯化中的应用做了综述。
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| 关 键 词： | 抗体纯化 色谱 嗜硫吸附 |
| 文章编号： | 1000-8713（2006）01-0088-05 |
| 收稿时间： | 2004-12-15 |
| 修稿时间： | 2004年12月15 |
Development and Application of Thiophilic Adsorption Chromatography for Antibody Purification |
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| LIU Xuan,SONG Hongxin.Development and Application of Thiophilic Adsorption Chromatography for Antibody Purification[J].Chinese Journal of Chromatography,2006,24(1):88-92. |
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| Authors: | LIU Xuan SONG Hongxin |
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| Institution: | Life Science & Engineering College, Shaanxi University of Science &Technology, Xianyang 712081, China |
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| Abstract: | Thiophilic adsorption chromatography binds antibodies and other proteins in the presence of high concentration of salt. When eluted by decreasing the salt concentration, the high purity and recovery of proteins can be achieved. It is a new chromatographic technology for the purification of proteins. The review introduces the method for the purification of antibodies and covers the development and application of the original technology. |
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| Keywords: | thiophilic adsorption chromatography antibody purification |
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