Molecular iodine-catalyzed and air-mediated tandem synthesis of quinolines via three-component reaction of amines, aldehydes, and alkynes |
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| Authors: | Xuejian LiZhenjun Mao Yanguang WangWeixiang Chen Xufeng Lin |
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| Affiliation: | Department of Chemistry, Zhejiang University, Zheda Road 38, Hangzhou 310027, China |
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| Abstract: | A one-pot synthesis of quinolines via molecular iodine-catalyzed and air-mediated tandem condensation/imino-Diels-Alder/isomerization/oxidation of simple readily available amines, aldehydes, and alkynes has been developed. This methodology was extended to synthesize quinazolines from two molecules of amines and two molecules of glyoxalates. |
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| Keywords: | Molecular iodine Quinolines Multicomponent reaction Quinazolines |
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