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Transformations of chromanol and tocopherol and synthesis of ascorbate conjugates
Authors:Martina LahmannJoachim Thiem
Institution:University of Hamburg, Faculty of Science, Department of Chemistry, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany
Abstract:α-Tocopherol and as a model compound pentamethylchromanol could be transferred into simple and more complex 5a-ether derivatives including galactopyranose as well as ascorbic acid conjugates. Following elaboration of a glucopyranoside spacer element this could be used for tethering the vitamin E and the vitamin C components to give novel conjugates for subsequent biostudies concerning their proposed synergism of antioxidant properties in tissues.
Keywords:6-Chromanol  α-Tocopherol  Ascorbate  Glucopyranoside spacer element  Conjugates
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