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Efficient copper-catalyzed C-S cross-coupling of heterocyclic thiols with aryl iodides
Authors:Liang-Feng NiuYan Cai  Chao LiangXin-Ping Hui  Peng-Fei Xu
Affiliation:State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China
Abstract:A copper-catalyzed cross-coupling of heterocyclic thiols with aryl iodides is reported. The reaction was carried out in the presence of CuI (5 mol %), 1,10-phenanthroline (10 mol %) and K2CO3 (1.3 equiv) in DMF at 120 °C. A variety of heterocyclic sulfides were prepared in high selectivities and yields.
Keywords:Sulfide   Copper(I) iodide   Aryl iodide   1,10-Phenanthroline
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