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A novel multicomponent approach to the synthesis of 1,3-thiazolidine-2-thiones |
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| Authors: | Abdolali Alizadeh Nasrin ZohrehHamideh Sabahnoo Zohreh Noaparast |
| Institution: | Department of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran |
| Abstract: | An easy, efficient, and simple one-pot approach for the synthesis of 1,3-thiazolidine-2-thiones via multicomponent reaction is reported. The reaction of a primary amine with carbon disulfide in the presence of dibenzoylacetylene or bis(4-methyl-1-benzoyl)acetylene in a mixture of CH2Cl2 and H2O after 5 h, afforded the title compound as alkene diastereomers. |
| Keywords: | 1 3-Thiazolidine-2-thiones Primary amine Carbon disulfide Multicomponent reaction |
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