Application of an optimized dispersive nanomaterial ultrasound‐assisted microextraction method for preconcentration of carbofuran and propoxur and their determination by high‐performance liquid chromatography with UV detection |
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Authors: | Saeid Khodadoust Mohammad Sharif Talebianpoor Mehrorang Ghaedi |
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Affiliation: | 1. Medicinal plants Research Center, Yasuj University of Medical Science, , Yasuj, Iran;2. Department of chemistry, Yasouj University, , Yasouj, Iran |
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Abstract: | An extraction method based on dispersive nanomaterial ultrasound‐assisted microextraction was used for the preconcentration of carbofuran and propoxur insecticides in water samples prior to high‐performance liquid chromatography with UV detection. ZnS:Ni nanoparticles were synthesized based on the reaction of the mixture of zinc acetate and nickel acetate with thioacetamide in aqueous media and then loaded on activated carbon (ZnS:Ni‐AC). Different methods were used for recognizing the properties of ZnS:Ni‐AC and then this nanomaterial was used for extraction of carbamate insecticide as new adsorbent. The influence of variables on the extraction method (such as amount of adsorbent (mg: NiZnS‐AC), pH and ionic strength of sample solution, vortex and ultrasonic time (min), ultrasound temperature and desorption volume (mL) was investigated by a screening 27–4 Plackett–Burman design. Then the significant variables were optimized by using a central composite design combined with a desirability function. At optimum conditions, this method had linear response >0.0060–10 μg/mL with detection limit 0.0015 μg/mL and relative standard deviations <5.0% (n = 3). |
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Keywords: | Central composite design Dispersive nanomaterial ultrasound‐assisted microextraction High‐performance liquid chromatography Insecticides Plackett– Burman design |
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