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Kinetics of Degradation of Biapenem
Authors:JUDYTA CIELECKA‐PIONTEK  PRZEMYSŁAW ZALEWSKI  PIOTR GARBACKI  EWELINA JURA  ALICJA TALACZYŃSKA
Institution:Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Poznan University of Medical Sciences, , 60–780 Poznań, Poland
Abstract:The kinetic and thermodynamic analysis of biapenem degradation was conducted during acid–base hydrolysis, under the influence of buffer components and in the solid state at increased temperature (dry air) and relative air humidity (RH > 50%). The effects of the initial concentration of biapenem and the formation of degradation products on its stability were investigated.
Keywords:
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