Design, synthesis and antiviral potential of 14-aryl/heteroaryl-14H-dibenzo[a,j]xanthenes using an efficient polymer-supported catalyst |
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Authors: | Reddi Mohan Naidu Kalla Satheesh Krishna Balam Anil Kumar Mungara Arulselvan Palanisamy Ibrahim Khalivulla Shaik Lasekan Ola |
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Institution: | Department of Food Technology, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. |
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Abstract: | Polyethyleneglycol bound sulfonic acid (PEG-OSO?H), a chlorosulphonic acid-modified polyethylene glycol was successfully used as an efficient and eco-friendly polymeric catalyst in the synthesis of 14-aryl/heteroaryl-14H-dibenzoa,j]xanthenes obtained from the reaction of 2-naphthol and carbonyl compounds under solvent-free conditions with short reaction times and excellent yields. The biological properties of these synthesized title compounds revealed that compounds 3b, 3c, 3f and 3i showed highly significant anti-viral activity against tobacco mosaic virus. |
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