One-step synthesis of substituted 6-amino-5-cyanospiro-4-(piperidine-4')- 2H,4H-dihydropyrazolo[3,4-b]pyrans |
| |
| Authors: | Shestopalov Anatoliy M Emeliyanova Yuliya M Shestopalov Aleksandr A Rodinovskaya Lyudmila A Niazimbetova Zukhra I Evans Dennis H |
| |
| Institution: | N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 117913 Moscow, Russia. |
| |
| Abstract: | Three-component condensation of 4-piperidinones (7), 5-pyrazolones (8), and malononitrile (4) proceeds chemically and electrochemically and is a convenient one-step means of synthesis of substituted 6-amino-5-cyanospiro-4-(piperidine-4')-2H,4H-dihydropyrazolo3,4-b]pyrans (12). The electrochemical reactions proceed under milder conditions and with yields 12-15% greater than those of the reactions catalyzed by chemical bases. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
