Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes |
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| Authors: | Ge Wu Jun Zhou Min Zhang Peng Hu Weiping Su |
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| Affiliation: | State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China. wpsu@fjirsm.ac.cn. |
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| Abstract: | Using CuBr(2) as an additive, the Pd-catalyzed intermolecular C-H-C-H cross-coupling between benzoxazoles and unactivated simple arenes has been developed. This protocol provides a straightforward approach for the biological activity of 2-arylbenzoxazole derivatives. |
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