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Cytotoxic Diarylheptanoids from Pericarps of Juglans Cathayensis Dode
Authors:LI Yi-xiu  RUAN Han-li  ZHOU Xue-feng  ZHANG Yong-hui  PI Hui-fang  WU Jizhou
Institution:Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, P R. China
Abstract:A novel diarylheptanoid,named Jugcathanin(1),along with two known diarylheptanoids(2,3),were isolated from the fresh pericarps of Juglans Cathayensis Dode,A known triterpene(4) and a known aphthaoquinone(5) were also isolated from the plant,Their structures were elucidated on the basis of spectroscopic studies,All the compounds exhibited moderate cytotoxicities against human Hela,HepG2,and HL-60 cell lines.
Keywords:Juglans Cathayensis Dode  Jugcathanin  Antitumor activity
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