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Studies on cyclic dipeptides,I: Aryl modifications ofcyclo-[Phe-His]
Authors:C. R. Noe  A. Weigand  S. Pirker
Affiliation:(1) Institut für Pharmazeutische Chemie, Christian-Doppler-Laboratorium für Chemie Chiraler Verbindungen, Johann-Wolfgang-Goethe-Universität Frankfurt, D-60439 Frankfurt/Main, Germany
Abstract:Summary Seven new cyclic dipeptides have been synthesized and tested for their applicability as tools to elucidate the mechanism of formation of mandelonitrile with (SS)-cyclo-[Phe-His] type catalysts. Conformational analyses based on1H NMR spectra are presented for all prepared cyclic dipeptides.Dedicated to Prof. Dr. Dres. h.c.Herbert Oelschläger on the occasion of his 75th birthday
Keywords:(SS)-cyclo-[Phe-His]  Hydrocyanation  Conformational analysis
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