RATIOING FLUOROMETER PROBE FOR LOCALIZING CARCINOMA IN SITU IN BRONCHI OF THE LUNG |
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| Authors: | Oscar J. Balchum A. Edward Profio Nicholas Razum |
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| Affiliation: | Pulmonary Disease Service, Department of Medicine, Los Angeles County/USC Medical Center, 2025 Zonal Avenue, GNH 11-240, Los Angeles, CA 90033, USA;The Department of Chemical and Nuclear Engineering, University of California at Santa Barbara, Santa Barbara, CA 93106, USA |
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| Abstract: | Abstract A bronchoscopic ratioing fiuorometer probe, that ratios the red light emitted from bronchial tumor to the green light of autofluorescence upon stimulation by violet light (413 nm) has proven capable of detecting and localizing small bronchial tumors bronchoscopically, 4, 48, and 72 h after intravenous Photofrin II injection. Still to be determined is whether'field averaging'in the case of very small bronchial carcinoma in situ will diminish accuracy. The accuracy, efficiency, and cost of localization by imaging fluorescence bronchoscopy will be compared to that by non-imaging ratioing fiuorometer probe. |
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