6,6-Heptamethylenetetrahydropyran-2,4-dione in the Synthesis of Benzo[f]pyrano[3,4-b]quinolines and Pyrano[4,3-b][4,7]phenanthrolines |
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Authors: | Kozlov N. G. Pashkovskii F. S. Gusak K. N. Koroleva E. V. Tereshko A. B. Lokot’ I. P. |
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Affiliation: | (1) Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, Minsk, 220072, Belarus;(2) Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, ul. Akademika Kuprevicha 5/2, Minsk, 220141, Belarus |
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Abstract: | Three-component condensation of 6,6-heptamethylenetetrahydropyran-2,4-dione with 2-amino-naphthalene or 6-aminoquinoline and aromatic aldehydes in an aliphatic alcohol afforded 12-aryl-9,9-hepta-methylene-8,9,10,12-tetrahydro-7H-benzo[f]pyrano[3,4-b]quinolin-11-ones and 12-aryl-9,9-heptamethylene-8,9,10,12-tetrahydro-7H-pyrano[4,3-b][4,7]phenanthrolin-11-ones, new N,O-heterocycles which include azaor diazaphenanthrene system fused to -pyrone ring and aromatic and spiro substituents. |
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