Design of Ligands for Affinity Purification of G-CSF Based on Peptide Ligands Derived from a Peptide Library |
| |
Authors: | FANG Rui ZHANG Chang-dong WANG Li-pin ZHOU Hui LI Wei |
| |
Affiliation: | College of Life Science, Jilin University, Changchun 130023, P. R. China |
| |
Abstract: | Combinatorial peptide libraries have become powerful tools to screen functional ligands by the principle of affinity selection. We screened in a phage peptide library to investigate potential peptide affinity ligands for the purification of human granulocyte colony-stimulation factor(hG-CSF). Peptide ligands will be promising to replace monoclonal antibodies as they have advantages of high stability, efficiency, selectivity and low price. |
| |
Keywords: | rhG-CSF Peptide Library Affinity Purification |
本文献已被 CNKI 等数据库收录! |
| 点击此处可从《高等学校化学研究》浏览原始摘要信息 |
|
点击此处可从《高等学校化学研究》下载全文 |