Enhancing fluorescence detection with a photonic crystal structure in a total-internal-reflection configuration |
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Authors: | Ye Jing Yong Ishikawa Mitsuru |
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Institution: | Center for Ultrafast Optical Science, University of Michigan, 2200 Bonisteel Boulevard, Ann Arbor, Michigan 48109-2099, USA. jyye@umich.edu |
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Abstract: | In contrast to fluorescence enhancement of fluorophores embedded in a photonic crystal structure as previously reported Appl. Phys. Lett. 75, 3605 (1999)], in this Letter we demonstrate a unique approach to forming an open microcavity using a one-dimensional photonic crystal in a total-internal-reflection geometry. This configuration opens up the possibility for enhancing fluorescence imaging and biosensing. Time-resolved fluorescence detection of fluorophores immobilized on the open cavity has been carried out. Over 20-fold fluorescence enhancement was observed. |
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