| 羟基取代的多环芳烃与一氧化氮的反应研究 |
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| 引用本文： | 雷连娣,张虹锐,杨得锁,吴隆民.羟基取代的多环芳烃与一氧化氮的反应研究[J].高等学校化学学报,2004,25(10):1863-1865. |
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| 作者姓名： | 雷连娣 张虹锐 杨得锁 吴隆民 |
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| 作者单位： | 1. 兰州大学功能有机分子化学国家重点实验室, 兰州730000;
2. 北京大学医学部医药卫生分析中心, 北京100083 |
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| 基金项目： | 国家自然科学基金 (批准号 :2 0 0 72 0 13 )资助 . |
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| 摘 要： | 内源性的一氧化氮(NO)是多种生理过程中必不可少的信使分子，它在神经系统递质传导、神经发育、脑血流调节以及免疫调节等过程中具有十分重要的作用。为揭示NO生理功能的化学本质，NO成为化学家近年来研究的重要课题之一。
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| 关 键 词： | 一氧化氮 羟基取代的多环芳烃 硝化 |
| 文章编号： | 0251-0790(2004)10-1863-03 |
| 收稿时间： | 2003-09-09 |
Reaction of Hydroxy-substituted Polycyclic Aromatic Hydrocarbons with Nitric Oxide |
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| LEI Lian-Di,ZHANG Hong-Rui,YANG De-Suo,WU Long-Min.Reaction of Hydroxy-substituted Polycyclic Aromatic Hydrocarbons with Nitric Oxide[J].Chemical Research In Chinese Universities,2004,25(10):1863-1865. |
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| Authors: | LEI Lian-Di ZHANG Hong-Rui YANG De-Suo WU Long-Min |
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| Institution: | State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China |
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| Abstract: | The reaction of a series of hydroxy-substituted polycyclic aromatic hydrocarbons(PAHs)with nitric oxide containing trace O 2 was carried out in CH 2Cl 2 at room temperature. The products identified by IR, NMR and HRMS indicate that the mono nitration at para- or ortho-position with respect to hydroxy group on the benzene ring occurred regioselectively. The reactions are assumed to be initiated by single electron transfer and the reaction intermediates may be resonance stabilized phenoxy-like radicals. |
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| Keywords: | Nitric oxide Hydroxyl-substituted polycyclic aromatic hydrocarbons Nitration |
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