| Abstract: | The alkylation of 6-methyl-4-methoxymethyl-3-cyano-2-(1H)pyridinethione by halogen derivatives in the presence of KOH proceeds regioselectively with the formation of S-alkyl derivatives. By cathodic electrolysis of the thiols in the presence of 6-methyl-4-methoxymethyl-2-chloro-3-cyanopyridine, 2-arylthiopyridines are obtained. By Thorpe-Ziegler cyclization of 2-alkylthiopyridines having an ctive methylene group, 2-aminothieno2,3-b]pyridines have been synthesized.Kuban State Technological University, Krasnodar, 350072. N. D. Zelinskii Institute of Organic Chemistry, Moscow 117913. Southern Branch of Association Rosvuznauka, Krasnodar, 350072. Translated from Khimiya Geterotsiklicheskikh Soedinenii, NO. 10, pp. 1432–1437, October, 1996. Original article submitted April 2, 1996; revision submitted August 20, 1996. |
