| 泰必利的极谱行为及其吸附特性 |
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| 引用本文： | 曾泳淮,曹洪国. 泰必利的极谱行为及其吸附特性[J]. 应用化学, 1997, 0(4): 108-110 |
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| 作者姓名： | 曾泳淮 曹洪国 |
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| 作者单位： | 北京师范大学化学系, 北京 100875 |
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| 摘 要： | 泰必利(Tiapridum, 简称 TIA)属苯酰胺类抗精神病药, 化学名称为 N -(2-二乙胺乙基)-2-甲氧基-5-甲烷磺酰基苯甲酰胺盐酸盐. 其极谱行为的研究未见报道, 本文用多种电化学手段研究了 TIA 在汞电极上的电化学行为, 对其吸附特性进行了探讨, 建立了单扫示波极谱测定法。
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| 关 键 词： | 泰必利 极谱行为 吸附 测定 |
| 收稿时间： | 1996-09-23 |
| 修稿时间： | 1997-05-05 |
Electrochemical Behavior and Adsorptive Properties of Tiapride |
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| Zeng Yonghuai,Cao Hongguo. Electrochemical Behavior and Adsorptive Properties of Tiapride[J]. Chinese Journal of Applied Chemistry, 1997, 0(4): 108-110 |
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| Authors: | Zeng Yonghuai Cao Hongguo |
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| Affiliation: | Department of Chemistry, Beijing Normal University, Beijing 100875 |
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| Abstract: | In a supporting electrolyte of HAc-NaAc, a sensitive derivative reduction peak of Tiapride was found by single-sweep oscillopolarography. The peak potential is -1.56 V( vs.SCE). The relationship between the peak current and the concentration of Tiapride is linear from 6.0×10-7～9.0×10-6 mol/L. The detection limit is 5.0×10-7 mol/L. The method was applied for determination of Tiapride in tablet with satisfactory results. The electrode process, reaction mechanism and polarographic behavior have been discussed. |
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| Keywords: | Tiapride polarographic behavior adsorption determination |
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