Highly Efficient Adsorption of Bilirubin by Ti3C2Tx MXene |
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| Authors: | Xiaoyu Sun Dr. Jian Yang Prof. Dawei Su Prof. Chengyin Wang Prof. Guoxiu Wang |
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| Affiliation: | 1. The College of Chemistry and Chemical Engineering, Yangzhou University, 180 Si-Wang-Ting Road, Yangzhou, 225002 P. R. China;2. Centre for Clean Energy Technology, School of Chemistry and Forensic Science, Mathematical and Physical Science, University of Technology Sydney, City Campus, Broadway, Sydney, NSW 2007 Australia |
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| Abstract: | We discovered that the 2D Ti3C2Tx MXene sheet displays an ultra-high removal capability for bilirubin (BR). In particular, MXene shows 47.6 times higher removal efficiency over traditional activated carbon absorbents. The effect of MXene on the removal rate of BR in BR solution containing different concentrations of bovine serum albumin (BSA) was studied. The adsorption capacity of BSA for BR at high concentration of 5 g L−1 was about 85% of the best adsorption capacity. The MXene before and after adsorption was characterized by SEM, FT-IR and XPS. Furthermore, MXene beads were prepared, and the hemoperfusion simulation experiment was carried out. The results show that the adsorption capacity of MXene for bilirubin can reach 1192.9 mg g−1. This study suggests that MXene may be promising in the treatment of hyperbilirubinemia. |
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| Keywords: | Mxene bilirubin hemoperfusion adsorbent hyperbilirubinemia |
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