Affiliation: | 1. Department of Applied Chemistry, National Chiao Tung University, Hsinchu, 30010 Taiwan Department of Materials Science and Engineering, Indian Institute of Technology Delhi, New Delhi, 110016 India;2. Department of Applied Chemistry, Centre of Emergent Functional Matter Science, National Chiao Tung University, Hsinchu, 30010 Taiwan;3. Department of Materials Science and Engineering, Indian Institute of Technology Delhi, New Delhi, 110016 India;4. Department of Applied Chemistry, National Chiao Tung University, 30010 Hsinchu City, Taiwan |
Abstract: | Fluorescence imaging, particularly in the NIR-II region (1000–1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use. |