首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Synthesis of functionalized pyrroles via catalyst- and solvent-free sequential three-component enamine-azoene annulation
Authors:Attanasi Orazio A  Favi Gianfranco  Mantellini Fabio  Moscatelli Giada  Santeusanio Stefania
Institution:Istituto di Chimica Organica, Universita? degli Studi di Urbino Carlo Bo, Via I Maggetti 24, 61029 Urbino, Italy.
Abstract:A new and efficient synthesis of polysubstituted pyrroles by a sequential one-pot three-component reaction between primary aliphatic amines, active methylene compounds, and 1,2-diaza-1,3-dienes (DDs) is reported. The reactions were performed without catalyst and under solvent-free conditions with complete control of pathway selectivity. Notably, the ready availability of the starting materials and the high level of practicability of the reaction and work up make this approach an attractive complementary method for access to unknown polysubstituted pyrroles.
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号