Fluorescent Properties of Some Thia- and Oxacarbocyanine Dyes in the Presence of DNA |
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| Authors: | M Yu Anikovsky A S Tatikolov V A Kuzmin |
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| Institution: | (1) Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119991, Russia |
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| Abstract: | Spectral and fluorescent properties of some thia- and oxacarbocyanine dyes were studied in the presence of DNA. Interaction of the dyes with DNA led to complex formation. A significant increase in the fluorescence quantum yield of the dyes in the presence of DNA was observed. The influence of a heteroatom and a substituent in the meso-position of the polymethine chain on the fluorescence growth was investigated. The stoichiometry of the strongly fluorescent dye–DNA complex was determined. |
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