A simple, two-step, site-specific preparation of fluorinated naphthalene and phenanthrene derivatives from fluorobromo-substituted alkenes |
| |
| Authors: | Wang Yi Xu Jianjun Burton Donald J |
| |
| Institution: | Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA. |
| |
| Abstract: | A facile two-step procedure for the site-specific preparation of fluorinated naphthalene and phenanthrene derivatives is described. The Sonogashira reaction of bromofluoro-substituted alkenes with terminal alkynes, followed by base-catalyzed cyclization in refluxing N-methyl-2-pyrrolidinone (NMP), affords the corresponding fluorinated naphthalene and phenanthrene derivatives in good yields. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
