Simple and efficient nickel-catalyzed cross-coupling reaction of alkynylalanes with benzylic and aryl bromides |
| |
Authors: | Biradar Deepak B Gau Han-Mou |
| |
Affiliation: | Department of Chemistry, National Chung Hsing University, Taichung, 402, Taiwan. |
| |
Abstract: | Highly efficient and simple coupling reactions of benzylic and aryl bromides with aluminium acetylide catalyzed by NiCl(2)(PPh(3))(2) are reported. The coupling reactions proceed at room temperature employing 4 mol% catalyst, affording coupling products in excellent yields of up to 95% in short reaction times. The system worked efficiently with aryl and heterocyclic bromides as well. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|