| Glucose
biosensor enhanced by nanoparticles |
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| 作者姓名： | 唐芳琼 孟宪伟 陈东 冉均国 郑昌琼 |
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| 作者单位： | TANG Fangqiong,CHEN Dong(Institute of Photographic Chemistry, Chinese Academy of Sciences, Beijing 100101, China);MENG Xianwei,RAN Junguo,ZHENG Changqiong(Inorganic Materials Department, Sichuan University, Chengdu 610065, China)
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| 摘 要： | Glucose biosensors have been formed with glucose oxidase (GOD) immobilized in composite immobilization membrane matrix, which is composed of hydrophobic gold, or hydro-philic gold, or hydrophobic silica nanoparticles, or the combination of gold and silica nanoparticles, and polyvinyl butyral (PVB) by a sol-gel method. The experiments show that nanoparticles can significantly enhance the catalytic activity of the immobilization enzyme. The current response can be increased from tens of nanoamperometer (nA) to thousands of nanoamperometer to the same glucose concentration, and the electrodes respond very quickly, to about 1 min. The function of nanoparticles effect on immobilization enzyme has been discussed.
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Glucose biosensor enhanced by nanoparticles |
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| TANG Fangqiong,CHEN Dong,MENG Xianwei,RAN Junguo,ZHENG Changqiong.Glucose
biosensor enhanced by nanoparticles[J].Science in China(Chemistry),2000,43(3):268-274. |
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| Authors: | TANG Fangqiong CHEN Dong MENG Xianwei RAN Junguo ZHENG Changqiong |
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| Institution: | 1. Institute of Photographic Chemistry, Chinese Academy of Sciences, Beijing 100101, China
2. Inorganic Materials Department, Sichuan University, Chengdu 610065, China |
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| Abstract: | Glucose biosensors have been formed with glucose oxidase (GOD) immobilized in composite immobilization membrane matrix, which is composed of hydrophobic gold, or hydro-philic gold, or hydrophobic silica nanoparticles, or the combination of gold and silica nanoparticles, and polyvinyl butyral (PVB) by a sol-gel method. The experiments show that nanoparticles can significantly enhance the catalytic activity of the immobilization enzyme. The current response can be increased from tens of nanoamperometer (nA) to thousands of nanoamperometer to the same glucose concentration, and the electrodes respond very quickly, to about 1 min. The function of nanoparticles effect on immobilization enzyme has been discussed. |
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| Keywords: | immobilization enzyme GOD Au nanoparticles SiO2 nanoparticles sensitivity |
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