Intermolecular [2+2+1] Carbonylative Cycloaddition of Aldehydes with Alkynes,and Subsequent Oxidation to γ‐Hydroxybutenolides by a Supported Ruthenium Catalyst |
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| Authors: | Dr. Hiroki Miura Kazuki Takeuchi Prof. Tetsuya Shishido |
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| Affiliation: | 1. Department of Applied Chemistry, Graduate School of Urban Environmental Sciences, Tokyo Metropolitan University, Minami‐Osawa, Hachioji, Tokyo 192‐0397 (Japan);2. Elements Strategy Initiative for Catalysts & Batteries (ESICB), Kyoto University, Kyoto 615‐8245 (Japan) |
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| Abstract: | Intermolecular [2+2+1] carbonylative cycloaddition of aldehydes with alkynes and subsequent oxidation to γ‐hydroxybutenolides is achieved using a supported ruthenium catalyst. A ceria‐supported ruthenium catalyst promotes the reaction efficiently, even with an ambient pressure of CO or without external CO, thus giving the corresponding γ‐hydroxybutenolide derivatives in good to high yields. Moreover this catalyst can be reused with no loss of activity. |
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| Keywords: | carbonylation cycloaddition heterocycles ruthenium supported catalyst |
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