Azulenesulfonium Salts: Accessible,Stable, and Versatile Reagents for Cross‐Coupling |
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Authors: | Paul Cowper Yu Jin Michael D Turton Dr Gabriele Kociok‐Köhn Dr Simon E Lewis |
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Institution: | 1. Department of Chemistry, University of Bath, Bath, UK;2. Chemical Characterisation and Analysis Facility, University of Bath, Bath, UK |
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Abstract: | Azulenesulfonium salts may be readily prepared from the corresponding azulenes by an SEAr reaction. These azulene sulfonium salts are bench‐stable species that may be employed as pseudohalides for cross‐coupling. Specifically, their application in Suzuki–Miyaura reactions has been demonstrated with a diverse selection of coupling partners. These azulenesulfonium salts possess significant advantages in comparison with the corresponding azulenyl halides, which are known to be unstable and difficult to prepare in pure form. |
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Keywords: | azulenes sulfonium salts sulfoxides Suzuki– Miyaura cross-coupling synthetic methods |
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