| 美丽红豆杉二萜的研究 II: 一个新的紫杉烷二萜的结构 |
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| 引用本文： | 梁敬钰,闵知大,丹羽正武. 美丽红豆杉二萜的研究 II: 一个新的紫杉烷二萜的结构[J]. 化学学报, 1988, 46(10): 1053-1054 |
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| 作者姓名： | 梁敬钰 闵知大 丹羽正武 |
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| 作者单位： | 中国药科大学植化教研室;日本名城大学 |
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| 摘 要： | 报导了从美丽红豆杉茎皮中分到的两个紫杉烷二萜化合物: 经高分辨核磁共振和COSY测定其结构为红豆杉素J(taxinine J)和2-去乙酰氧基-红豆杉素J(2-deacetoxytaxinine J), 后者系一新化合物, 药理结果表明: 二个化合物对肝癌细胞具有不同程度抑制作用.
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| 关 键 词： | 抗癌药 萜类化合物 质子磁共振谱法 红豆杉科 红豆杉素 |
Studies on the diterpenes of taxus mairei II: Structure of 2-deacetoxy-taxinine |
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| LIANG JINGYU,MIN ZHIDA,DAN YUZHENGWU. Studies on the diterpenes of taxus mairei II: Structure of 2-deacetoxy-taxinine[J]. Acta Chimica Sinica, 1988, 46(10): 1053-1054 |
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| Authors: | LIANG JINGYU MIN ZHIDA DAN YUZHENGWU |
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| Abstract: | A new taxane diterpene (I) and the known taxinin J (II) have been isolated from the bark of T. mairei collected in Fujian Province. The structure of I was determine to be 2-deacetoxytaxinin J on the basis of spectral anal. Both I and II were shown to possess inhibitory activity on hepatoma cell in vitro. |
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| Keywords: | ANTICARCINOGEN TERPENE PROTON MAGNETIC RESONANCE SPECTROMETRY TAXACEAE TAXININE |
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