Preparation of organometallic uracil-analogue Fischer carbene complexes: Comparative study of conventional heating vs microwave irradiation |
| |
| Authors: | Antonietta Artillo Marco De Santis Susagna Ricart Aldo Spinella |
| |
| Institution: | a Dipartimento di Chimica, Università di Salerno, Via Ponte Don Melillo, Fisciano-84084-Salerno, Italy
b Departament de Materials Moleculars, Institut de Ciencia de Materials de Barcelona (CSIC), Campus de la UAB, E-08193 Bellaterra, Spain |
| |
| Abstract: | Mono and disubstituted ureas react with alkynyl Fischer carbene complexes to give mono and di N,N-substituted organometallic uracil analogues. An optimization of the process using different starting metal carbene complexes and variously substituted ureas under conventional heating (with and without solvent) and microwave irradiation techniques is reported. The synthesis of the metal-carbene analog of the commercially available dimethyl uracil is reported. |
| |
| Keywords: | Biorganometallic chemistry Carbene complex Uracil analogues Microwave irradiation Ureas |
| 本文献已被 ScienceDirect 等数据库收录！ |
