Synthetic "chaperones": nanoparticle-mediated refolding of thermally denatured proteins |
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Authors: | De Mrinmoy Rotello Vincent M |
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Affiliation: | Department of Chemistry, University of Massachusetts at Amherst, Amherst, MA 01003, USA. |
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Abstract: | Thermally denatured chymotrypsin, lysozyme and papain are substantially refolded towards their native conformation by gold nanoparticle bearing dicarboxylate sidechains. |
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