A dynamical model of echinococcosis with optimal control and cost-effectiveness |
| |
Institution: | 1. University of Salford, Greater Manchester, United Kingdom;4. University of Zurich, Zurich, Switzerland;5. University of Melbourne, Werribee, VIC, Australia |
| |
Abstract: | A dynamical model of echinococcosis transmission with optimal control strategies is first presented. The basic reproduction number of the model is determined and employed to study the global stability of the disease-free and endemic equilibrium points. The optimal control problem is formulated and solved analytically. Numerical simulations show that optimal control strategies could effectively reduce the transmission of echinococcosis. The cost-effectiveness analysis suggests that a combination of health education, anthelmintic treatment, and home slaughter inspection could provide the best cost-effective strategy to control the transmission of echinococcosis. Furthermore, it finds that anthelmintic treatment and environmental disinfection may shorten the time of eliminating the disease. The results may be helpful for prevention and control of echinococcosis in Ganzi Tibetan Autonomous Prefecture, China and other areas of echinococcosis. |
| |
Keywords: | Echinococcosis Basic reproduction number Global stability Optimal control Cost-effectiveness |
本文献已被 ScienceDirect 等数据库收录! |
|