The intein of the Thermoplasma A-ATPase A subunit: Structure, evolution and expression in E. coli |
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| Authors: | Alireza G Senejani Elena Hilario J Peter Gogarten |
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| Institution: | (1) Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269-3044, USA;(2) HortResearch, 120 Mt Albert Road, Private Bag 92, 169 Mt Albert, Auckland, New Zealand;(3) Department of Molecular and Cell Biology, University of Connecticut, 75 North Eagleville Rd, Storrs, CT 06269-3044, USA |
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| Abstract: | Background Inteins are selfish genetic elements that excise themselves from the host protein during post translational processing, and
religate the host protein with a peptide bond. In addition to this splicing activity, most reported inteins also contain an
endonuclease domain that is important in intein propagation. |
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