| Optimization of the separation of a mixture of unknown composition by reversed-phase HPLC |
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| 基金项目： | Project supported by the National Natural Science Foundation of China. |
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| 摘 要： | A method is presented for the computer-assisted optimization of mobile phaseselection for the separation of a synthetic intermediate of unknown composition by reversed-phase HPLC.The method is based on recognition of the order of the peaks by comparisonof peak area ratio and followed by the BSOS-L(Binary Solvent Optimization System forHPLC)method.Excellent agreement was obtained between predicted data and experimentalresults.
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Optimization of the separation of a mixture of unknown composition by reversed-phase HPLC |
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| Qin-Sun Wang,Ru-Yu Gao,Zhuang-Ping Zhan. Optimization of the separation of a mixture of unknown composition by reversed-phase HPLC[J]. Chinese Journal of Chemistry, 1993, 11(4): 329-334. DOI: 10.1002/cjoc.19930110406 |
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| Authors: | Qin-Sun Wang Ru-Yu Gao Zhuang-Ping Zhan |
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| Abstract: | A method is presented for the computer-assisted optimization of mobile phase selection for the separation of a synthetic intermediate of unknown composition by reversed-phase HPLC. The method is based on recognition of the order of the peaks by comparison of peak area ratio and followed by the BSOS-L (Binary Solvent Optimization System for HPLC) method. Excellent agreement was obtained between predicted data and experimental results. |
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